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Cellule staminali ed esosomi

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Cellule staminali ed esosomi

Studi Clinici

Staminali del Grasso

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Malattie Polmonari

2016 January A phase I study for intravenous autologous mesenchymal stromal cell administrationto patients with severe emphysema Mesenchymal stromal cells (MSCs) may reduce inflammation and promote tissue repair in pulmonary emphysema. LEGGI

2016 January Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonarydisease The increasingly high rates of morbidity and mortality due to acute and chronic lung diseases have emerged as one of the major public health issues globally. LEGGI

2016 January Health relevance of the modification of low grade inflammation in ageing (inflammageing) and therole of nutrition Ageing is characterised by an increase in the concentration of inflammatory markers in the bloodstream, a phenomenon that has been termed “inflammageing”. The inflammatory response is beneficial as an acute, transient reaction to harmful conditions, facilitating the defence, repair, turnover and adaptation of many tissues. However, chronic and low grade inflammation is likely to be detrimental for many tissues and for normal functions. LEGGI

2017 May Mesenchymal stem cells in idiopathic pulmonary fibrosis Idiopathic pulmonary fibrosis (IPF) is a major cause of respiratory failure in critically ill patients and common outcome of various lung interstitial diseases. LEGGI

2017 July Mesenchymal Stem Cells inFibrotic Disease Fibrosis is associated with organ failure and high mortality and is commonly characterized by aberrant myofibroblast accumulation. LEGGI

2017 August Adipose-derived stromal cell inregenerative medicine: A review. The application of appropriate cell origin for utilizing in regenerative medicine is the major issue. Various kinds of stem cells have been used for the tissue engineering and regenerative medicine. LEGGI

2017 August Autologous Stromal Vascular Fraction inthe Intravenous Treatment of End-StageChronic Obstructive Pulmonary Disease:A Phase I Trial of Safety and Tolerability Chronic obstructive pulmonary disease (COPD) is a consistently progressive, ultimately fatal disease for which no treat- ment exists capable of either reversing or even interrupting its course. LEGGI

2018 April Effects of different mesenchymal stromalcell sources and delivery routes inexperimental emphysema We sought to assess whether the effects of mesenchymal stromal cells (MSC) on lung inflammation and remodeling in experimental emphysema would differ according to MSC source and administration route. LEGGI

2018 April Mesenchymal stromal cell infusionmodulates systemic immunologicalresponses in stable COPD patients:A phase I pilot study COPD is characterised by tissue destruction and inflammation. Given the lack of curative treatments and the progressive nature of the disease, new treatments for COPD are highly relevant. LEGGI

2018 April Combined Bone Marrow‐Derived Mesenchymal Stromal Cell Therapy and One‐Way Endobronchial Valve Placementin Patients with Pulmonary Emphysema:A Phase I Clinical Trial One‐way endobronchial valves (EBV) insertion to reduce pulmonary air trapping has been used as therapy for chronic obstructive pulmonary disease (COPD) patients. LEGGI

2018 April Transplantation of adipose-derived mesenchymalstem cells attenuates pulmonary fibrosis of silicosisvia anti-inflammatory and anti-apoptosis effects inrats Silicosis has been topping the list of high-incidence occupational diseases in developing countries and cannot be completely cured. LEGGI

2018 July Mesenchymal Stem Cell Therapy of PulmonaryFibrosis: Improvement with Target Combination Although the clinical application of new drugs has been shown to be effective in slowing disease progression and improving the quality of life in patients with pulmonary fibrosis, the damaged lung tissue does not recover with these drugs. LEGGI

2018 July Clinical applications of mesenchymalstem cells in chronic lung diseases. Mesenchymal stem (stromal) cells (MSCs) are multipotent stromal cells that have the ability to modulate immune response to tissue injury and promote repair in vivo. LEGGI

2018 August Cell Therapy in Idiopathic PulmonaryFibrosis diopathic pulmonary fibrosis is a fatal disease with no effective or curative treatment options. LEGGI

2018 September Human Mesenchymal Stem CellSecretome from Bone Marrow or Adipose-DerivedTissue Sources for Treatment ofHypoxia-Induced Pulmonary EpithelialInjury Alveolar epithelial dysfunction induced by hypoxic stress plays a significant role in the pathological process of lung ischemia-reperfusion injury (IRI). LEGGI

2018 October Clinical Application of Mesenchymal StemCell-Derived Extracellular Vesicle-BasedTherapeutics for Inflammatory Lung Diseases It is currently thought that extracellular vesicles (EVs), such as exosomes and microvesicles, play an important autocrine/paracrine role in intercellular communication. LEGGI

2018 October Clinical observation of umbilical cord mesenchymal stem cell treatment ofsevere idiopathic pulmonary fibrosis:A case report Idiopathic pulmonary fibrosis (IPF) is a degenerative disease characterized by fibrosis. LEGGI

2018 November Off-label mesenchymal stromal cell treatment in two infants with severe bronchopulmonary dysplasia: clinicalcourse and biomarkers profile Bronchopulmonary dysplasia (BPD) is the most prevalent sequelae of premature birth, for which therapeutic options are currently limited. LEGGI

2018 November Mesenchymal Stem Cells for theTreatment of Idiopathic PulmonaryFibrosis Idiopathic pulmonary fibrosis (IPF) is an inexorably progressive lung disease of unknown origin LEGGI

2018 November Mesenchymal stromal cells: a noveltherapy for the treatment of chronicobstructive pulmonary disease? COPD is characterised by tissue destruction and inflammation. LEGGI

2018 December Stem Cell Delivery with Polymer HydrogelforTreatment of Intervertebral Disc Degeneration:From 3D Culture to Design of the Delivery Device for MinimallyInvasive Therapy. Nucleus pulposus (NP) tissue damage can induce detrimental mechanical strain on the biomechanical performance of intervertebral discs (IVDs), causing subsequent disc degeneration. LEGGI

Contenuti scientifici revisionati dal Comitato Scientifico di Bioscience Institute. · Ultimo aggiornamento 2025-05-05

Le informazioni in questa pagina hanno scopo divulgativo e non sostituiscono il consulto con un medico.

Cellule staminali ed esosomi

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Cellule staminali ed esosomi

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