To use the cord tissue stem cell storage service, simply send us an email at info@bioinst.com requesting the collection kit or fill out the online request form available in the “Order the Kit” section.
The Bioscience Institute staff will assist you in administrative procedures and, through its scientific committee, will provide you with all the information on the therapeutic use of stem cells and on the most recent developments in scientific research.
The Collection Kit will be sent by courier, complete with the necessary documentation. The Bioscience Institute staff will assist you in administrative procedures and will provide you with all the information on the therapeutic use of stem cells and on the most recent developments in scientific research.
The Collection Kit consists of the necessary equipment to carry out the collection of umbilical cord tissue and the documentation required to request the Export Authorization. It is kept in an isothermal case made of waterproof plastic resin, equipped with a pressurization valve for air transport and internally lined with polyurethane foam, which enables it to be resistant to the following*:
* The Collection Kit must comply with the IATA procedure PI 650 UN 3373 (Circular of the Ministry of Health No. 16 of 20 July 1994 “Recommendations for the transport safety of infectious materials and diagnostic samples”, Circular of the Ministry of Health No. 3 of 8 May 2003) and must also be easily visible/identifiable in compliance with the Ministerial Ordinance of 4 May 2007 and regional regulations.
The case contains the following:
On the day of admission, you will have to take the Collection Kit to the hospital and deliver it to the health care staff responsible for the delivery, who have been notified in advance. After the collection you will have to activate the ordinary procedure for the collection and shipment by contacting the Bioscience Institute immediately.
The bag will travel at room temperature in a highly protected, double isothermal container and does not require refrigerated vehicles. The shipment of cord blood to the Republic of San Marino will be constantly monitored according to dedicated and specially designed logistics, not requiring customs controls, and allowing flexible management of any problems related to holidays, strikes or adverse climatic situations.
If necessary, a dedicated courier will be activated which will guarantee the delivery of the biological material to the Bioscience Institute within the deadlines established by the Ministry of Health (“Guidelines for the accreditation of umbilical cord blood banks”) regardless of any adverse event.
Upon arrival of the Collection Kit, the Bioscience Institute staff will perform the procedures necessary for the separation of the stem cells contained in the umbilical cord tissue collected and then proceed with freezing and cryopreservation. Upon request, the cell sample can be divided and cryopreserved in two separate units (bags).
The cryopreservation has a minimum duration of 20 years, which will be automatically renewed for all the years for which the annual fee will be paid.
Request the Collection KIT to be sent by calling the Toll-Free Number 800 690 914 or by filling out the online request form available on the Order Kit page.
At least 30 days before the birth, contact the Health Department of the hospital to ascertain the steps necessary to obtain the Export Authorization.
No more than 30 days before delivery, perform the tests required by the legislation and Health Management of the hospital (the Health Management will only have to view the first 4 tests, marked with an asterisk *):
a. Anti-HIV 1 and 2 *
b. Anti HCV (hepatitis C) *
c. HBsAg (hepatitis B) *
d. Anti-HBc (IgG) * and Anti-HBc (IgM) *
e. TPHA (syphilis)
f. Anti- HTLV 1e 2 (T-lymphocyte lymphotropic virus)
Go back to the Health Department of the hospital for the issue of the Authorization, bringing with you the results of the 4 tests marked with an asterisk * (Step 3) and the Certificate of Compliance of the Collection Kit (“documents for the hospital” envelope contained in the Collection Kit).
Once the collection has been performed, Bioscience Institute will be informed and will take care of the collection of the sample directly at the hospital and its transport to the laboratories.
Once in the Bioscience Institute laboratories, the cord blood sample is subjected to tests and, if suitable, subject to the freezing procedure.
Cord blood is the blood that remains in the umbilical cord after the baby is born and is a valuable source of stem cells.
Until recently it was treated as “waste” and eliminated with hospital waste along with the placenta and the umbilical cord. It is currently used in the treatment of around 100 serious diseases.
