Erectile Dysfuction (ED) is one of the most frequently reported medical condition in men. Defined as the chronic inability to achieve or sustain the erection, its prevalence varies across age group, with 35% and 50% ca of men, respectively, aged 60 and older than 70 affected. However, it is not a natural part of getting older.
Stem Cells Treatment for Erectile Dysfuction (ED)
Erectile dysfunction, not only it could be a sign of some health problem (such as blood vessels clogging or nerve damage) but also it could severely compromise man’s quality of life (leaving him with low self-esteem, lack of self confidence, and poor-quality intimate life) and his partner’s mental, emotional, and physical wellbeing, ultimately leading to the risk of marital relation problems.
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Treatment Options
Treatments can be divided into traditional and novel approaches, the former including lifestyle changes, topical or oral medications, intracavernosal injections, intraurethral suppositories, vacuum-assisted erectile devices, and surgically implantable prostheses, and the latter consisting in innovative options such as external prosthesis, shockwave therapy, platelet-rich plasma injection and stem cell therapy.
Oral medications, in particular phosphodiesterase type-5 inhibitors (including sildenafil, vardenafil, tadalafil, and avanafil), are among the most prescribed treatments for erectile dysfunction. However, they only address the symptoms without eliminating the cause of the problem. Moreover, they work only if nervous system pathways are intact, they may lose effectiveness when used continuously, and their combination with other drugs (such as medications prescribed for chest pain or hypertension) can be contraindicated.
Erectile Dysfunction Causes
The main risk factors are linked to the vascular, nervous and endocrine system. In particular, certain diseases and conditions (such as cardiovascular problems, type 2 diabetes, obesity, metabolic syndrome, chronic kidney disease, bladder cancer surgery, and prostate cancer treatment-related injuries) can lead to erection problems.
Also many common medications (among others, antidepressants, tranquilizers, blood pressure medications, antiandrogens, appetite suppressants, and ulcer medications) can lead to erection problems.
Finally, psychological causes of erectile dysfunction include stress, anxiety, depression, low self-esteem, fear of sexual failure, guilt about sexual performance or activity. In general, unhealthy living is associated with an increase in the risk of erectile dysfunction. Other risk factors include specific gene variants, various markers of cardiovascular disease and several medical conditions, such as obstructive sleep apnea, ankylosing spondylitis, chronic prostatitis or pelvic pain syndrome, psoriasis, chronic periodontitis, and gout.
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Action
Scientific evidence
In a study that involved men with a history of prostatectomy, adipose stem cells-based therapy allowed erection successful for intercourse, without the need for oral medication, in almost 50% of cases.
In another study, 53% with prostatectomy-derived erectile dysfunction reported erection successful for intercourse.
Bibliography
Haahr MK et al. EBioMedicine. 2016 Jan 19;5:204-10. doi: 10.1016/j.ebiom.2016.01.024
Haahr MK et al. Urology. 2018 Nov;121:203.e6-203.e13. doi: 10.1016/j.urology.2018.06.018
Procedure
ANDROSKILL procedure, the stem cell therapy for erectile dysfunction by Bioscience Institute, is based on the collection of only 20 cc of fat during a quick and painless outpatient procedure.
Bioscience Laboratories receive the collected fat and expand the isolated stem cells in 3-4 weeks, obtaining several hundred million of pure autologous cells that can be used for erectile dysfunction treatment as well as for other procedures.
The cells that are not immediately utilized are frozen and cryopreserved for future treatment; cells are preserved for a minimum of 2 years, ready to be thawed for additional use.
