Umbilical cord blood is one of the best sources of NK cells: it is richer in them than peripheral blood and bone marrow, contains progenitors absent in peripheral blood, and requires simpler isolation procedures.
For this reason, in addition to making available a high quantity of hematopoietic stem cells, the cryopreservation of umbilical cord blood also guarantees a valuable reserve of NK cells for autologous use (i.e. by the same individual from which they were taken) or haploidentical (i.e. by relatives compatible to 50%).
Furthermore, thanks to methods based on GMP (Good Manufacturing Practice) standards, starting from cryopreserved umbilical cord blood samples, it is possible to obtain large quantities of functional NK cells.