Aging, inflammation and cancer.
In the intrinsic pathway, genetic events that cause neoplasia (oncogenes and oncosupressor genes) orchestrate the construction of cancer-related inflammation.
RANK–RANKL signalling in cancer
Oncogenic events combined with a favourable environment are the two main factors in the oncological process.
Leveraging natural killer cells for cancer immunotherapy
Although T cells receive much of the clinical and preclinical attention when it comes to cancer immunotherapy, new strategies are utilizing adoptive NK-cell immunotherapy and monoclonal antibodies and engineered molecules which have been developed to specifically activate NK cells against tumors.